The New York Yankees welcome the St. Louis Cardinals to Yankee Stadium on Wednesday, August 5, 2026 for a 7:05 PM ET first pitch. Will Warren gets the ball for New York against Cardinals right-hander Andre Pallante in what shapes up as a compelling mid-rotation matchup. The game is available nationally on Amazon Prime Video and locally on WFAN 660/101.9 FM, with Spanish-language coverage on WADO 1280. August baseball at The Bronx means every game carries real stakes — the Yankees need to take care of business at home.

Starting Pitchers: Will Warren vs. Andre Pallante

Will Warren draws the assignment for the Yankees. The right-hander has been working to establish himself as a reliable arm in New York's rotation, and a home start against the Cardinals presents a real opportunity to make a statement. Warren will need sharp command and the ability to get ahead in counts against a Cardinals lineup that makes contact.

Andre Pallante takes the hill for St. Louis. The right-hander is known for his ground-ball tendencies and his ability to pitch to contact — qualities that can be effective but also dangerous if New York gets the ball rolling. The Yankees' lineup will look to work counts and punish any mistakes early.

Yankees Lineup Breakdown

Manager Aaron Boone is running out a lineup built around athleticism and depth. Trent Grisham leads off from center field, setting the table for Ben Rice hitting second as the designated hitter. Luis García Jr. slots in at first base batting third, followed by Heliot Ramos in left field hitting cleanup. Spencer Jones gets the five-hole in right field, with Jazz Chisholm Jr. batting sixth at second base. Ryan McMahon holds down third, George Lombard Jr. is at shortstop batting eighth, and Austin Wells rounds out the order behind the plate.

Cardinals Lineup Breakdown

St. Louis is going with a young, energetic group. JJ Wetherholt leads off at shortstop, with Iván Herrera batting second behind the plate. Alec Burleson hits third at first base, and José Fermín is in the four-hole in right field. Nathan Church hits fifth in center, Blaze Jordan bats sixth at third, Bryan Torres handles left field batting seventh, Jimmy Crooks is the designated hitter hitting eighth, and César Prieto wraps up the order at second base.

Keys to Watch for the Yankees

• Warren's command early: Getting ahead of Cardinals hitters in the first two innings will set the tone. Pallante is the type of pitcher who keeps games close, so the Yankees need to score before the bullpen equation becomes complicated.
• Middle of the order production: Heliot Ramos and Spencer Jones in the four and five spots have the power to do real damage against a ground-ball pitcher like Pallante. If Pallante is leaving balls up, those two need to make him pay.
• Jazz Chisholm Jr.'s at-bats: Batting sixth, Chisholm has the speed and bat to turn a big inning into a blowout. Keep an eye on how he handles Pallante's secondary stuff.
• Austin Wells behind the plate: Wells quarterbacking Warren's game plan matters as much as anything. His pitch-framing and game management are key to keeping Warren in rhythm.

Prediction

Yankee Stadium crowd on a Wednesday night in August is going to be locked in. If Will Warren can give New York five or six quality innings and the middle of the order does its job against Pallante, the Yankees take this one. The Cardinals lineup is young and has some interesting pieces, but the home-field edge and the firepower in New York's four and five holes should be the difference. Yankees 5, Cardinals 3.